White Innocuous Hydroxypropyl Cyclodextrin Oral Medications Eye And Nasal Preparations
Technical Parameter
Product Name: Hydroxypropyl Beta Cyclodextrin
Other Name: 2-Hydroxypropyl Beta Cyclodextrin,Hydroxypropyl Betadex,Hydroxypropyl Cyclodextrin
CAS NO.: 128446-35-5
Technical Standards
| Item | Specification |
| Classification | Injection Grade and Oral Grade |
| Escherichia coli | Absent |
| Conductivity | ≤200 |
| Application | Pharmaceuticals,Food,Cosmetics |
| Shelf life | 36 Months |
| Moisture | ≤6.0% |
| Solution clarity and color | Conform |
| Heavy metal | ≤0.0025% |
| Loss on Drying | ≤10.0% |
| Solubility | ≥100(25℃,g/100ml) |
| Appearance | White powder,sweet,insipid and innocuous |
| chloride | ≤0.05% |
| Quality | GMP standards |
| pH | 5.0~7.5 |
| Heavy Metals (ppm) | ≤10 |
| Propylene glycol | ≤2.5% |
| Beta-cyclodextrin | ≤0.5% |
| Any other single impurities | ≤0.25% |
Product Introduction
Natural Cyclodextrin:
- Alpha Cyclodextrin CAS 10016-20-3
- Beta Cyclodextrin CAS 7585-39-9
- Gamma Cyclodextrin CAS 17465-86-0
Cyclodextrin Derivatives & Compounds:
- Hydroxypropyl Beta Cyclodextrin Hydroxypropyl Beta Cyclodextrin Solution
- Piroxicam Beta Cyclodextrin 2,6-Dimethyl Beta Cyclodextrin
- Carboxymethyl Beta Cyclodextrin 2-Hydroxypropyl Beta Cyclodextrin
- Methyl Beta Cyclodextrin Glucosyl Beta Cyclodextrin
- Hydroxyethyl Beta Cyciodextrin
- Hydroxypropyl Alpha Cyclodextrin Hydroxypropyl Gamma Cyclodextrin
Product Features
1. Improve drug utilization.
2. Increase the water solubility of poorly soluble drugs.
For example: Dihydroartemisinin and artemether are insoluble in water. After being encapsulated with hydroxypropyl beta-cyclodextrin, their solubility can meet the requirements of powder injection. The solubility of digoxin in 100% hydroxypropyl beta-cyclodextrin solution is increased from 0.07mg/ml to 130mg/ml compared with that in water.
3. Reduce drug toxicity and side effects.
For example: The vasodilator drug nimodipine is insoluble in water and is susceptible to first-pass effects of the liver when taken orally. Using hydroxypropyl beta-cyclodextrin to make an injection for intramuscular administration can significantly increase the absorption of the drug by the organism and reduce damage to the gastrointestinal or muscle tissue.
4. Increase drug stability.
For example: After estradiol is encapsulated with hydroxypropyl beta-cyclodextrin and placed at room temperature, its degradation half-life can be extended from 1.2 years to 4 years.
5. Hydroxypropyl beta-cyclodextrin is very safe for organisms.
Product Description
Hydroxypropyl-β-cyclodextrin (HP-β-CD, HPBCD) is a type of hydroxyalkylated hydrophilic derivative formed by the condensation of β-CD and propylene oxide. It is a white or off-white amorphous or crystalline powder; odorless; strong hygroscopicity. This product is highly soluble in water or propylene glycol, easily soluble in methanol or ethanol, and almost insoluble in a.cetone or chloroform.
Hydroxypropyl beta-cyclodextrin is a hydroxyalkylated derivative of beta-cyclodextrin. It has excellent water solubility (the solubility at room temperature is greater than 500 mg/ml) and has a significant solubilizing effect on drugs that are difficult to dissolve in water. It has been used as a solubilizer for injections abroad.
Product Pictures
Product Packaging
Company Profile
ZIBO WEYES NEW MATERIALS CO.,LTD is a series of high-tech enterprises integrating scientific research, production and sales, specializing in research and production of cyclodextrin and derivatives, food and cosmetic additives, nutritional supplements and other plant extracts.The company has built an auxiliary material production workshop in line with cGMP, equipped with advanced inspection and testing instruments and equipment, constantly studying the inclusion technology, and providing comprehensive cyclodextrin application technology solutions and OEM services.
Company Certificate
Logistics
By air, by express(DHL,FedEx,UPS.etc), by sea or other modes of transportation.
We will discuss and provide samples according to customer needs.
FAQ
Q1. Can I have a sample order for HYDROXYPROPYL-BETA-CYCLODEXTRIN?
A: Yes, we welcome sample order to test and check quality. Mixed samples are acceptable.
Q2. What about the lead time?
A: 3-5 days for Sample preparing ,8-10 working days for mass production.
Q3. Do you have any MOQ limit for HYDROXYPROPYL-BETA-CYCLODEXTRIN order?
A: Low MOQ, 1kg for sample checking is available.
Q4. How do you ship the goods and how long does it take to arrive?
A: Ship by DHL, UPS, FedEx. It takes 3-5 days to arrive. Airline and sea shipping also optional.
Q5.What services do you have?
A:We provide excellent after-sales service; we offer productcustomization services.
Contract
ZIBO WEYES NEW MATERIALS CO.,LTD
Address:Pharmaceutical Innovation Park, high tech District, Zibo, Shandong, China
TEL/WhatsApp/Wechat: +86 190 5476 7765
Email:katrina@zbweyes.com
Contact: Katrina Jiang
Product Tags:
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White Hydroxy Beta Cyclodextrin Powder Oral Medications Cas 7585-39-9 Images
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